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New osmotic method for the removal of water from samples containing thermo-sensitive molecules

Martin Peet - Thursday, July 29, 2010
Current evaporation techniques are often not suitable for thermo-labile molecules such as proteins because of the high operating temperatures that are traditionally employed. Discovery is pleased to announce the introduction of the Evapeos from Ederna of France that promises to provide a more rapid, low temperature, atmospheric pressure solution for the removal of water from samples containing thermo-sensitive compounds. Key applications for the Evapeos are active pharmaceutical ingredient and natural product concentration.



The Evapeos utilizes a process called osmotic distillation to rapidly remove water from critical samples. This process involves the transfer of water (as a vapour) from a diluted aqueous medium toward an aqueous osmotic agent. These two miscible fluids are separated by a gas permeable, hydrophobic hollow fibre with high porosity. The difference in water activities between the two compartments leads to a high water vapour flux even at room temperature and at atmospheric pressure.



Evapeos evaporators are controlled through intuitive colour touch screens and use cartridges that contain thousands of hollow fibres to generate high water fluxes of up to 1 L per hour at 40°C. The unit does not require a vacuum and a range of different-sized FDA-approved cartridges are available to allow samples to be concentrated down from a sample size of up to 1 L to as low as 25 mL.  Separate cartridges can be used for different products in order to avoid cross-contamination.

More Information

Visit Discovery's main instrumentation web site for more information on the Evapeos or contact Discovery for pricing.


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